# NIH Reporter #5R01CA278802-04

TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumors

**Recipient:** National Cancer Institute (NCI), part of the NIH

**Award Amount:** $698,501.00
**Ceiling:** $698,501.00

**Awarded:** June 09, 2023

**Identifier:** 5R01CA278802-04

Research project funded by NIH/NCI to enhance liver-directed radiotherapy and immune checkpoint blockade using TLR5 pathway modulation for liver metastasis and abscopal tumors.

### Description

This project involves research on enhancing liver-directed radiotherapy and immune checkpoint blockade using TLR5 pathway modulation, with a focus on translational relevance in human tumors. The project is funded by the NIH/NCI and involves collaboration with Roswell Park Cancer Institute.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11324545)