Award
National Institute of Allergy and Infectious Diseases 3R01AI175941-04S1
Defining correlates of protection from dengue illness in a long-term cohort study of multigenerational house-holds in Thailand
Recipient
Upstate Medical University, Syracuse, NY, United States
Award Amount
$94,253.00
Ceiling
$94,253.00
Awarded
July 14, 2026
Identifier
3R01AI175941-04S1
A research project funded by NIAID to study immune correlates of protection against dengue illness using a long-term cohort in Thailand, aiming to improve dengue diagnostics and vaccines.
Description
This project aims to define how the early immune environment to DENV, shaped by maternally-transferred DENV antibodies and early exposures, influences future antibody profiles and risks of dengue illness. It leverages a long-term cohort study in Thailand with over 3000 individuals, including mother-infant dyads, to identify immune correlates of protection and inform vaccine development.