Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK072381-19
Kidney Injury Molecule-1 in Epithelial Repair
Recipient
BRIGHAM AND WOMEN'S HOSPITAL
Award Amount
$527,738.00
Ceiling
$527,738.00
Awarded
July 21, 2025
Identifier
5R01DK072381-19
Research project awarded to study Kidney Injury Molecule-1's role in kidney repair and chronic kidney disease treatment potential.
Description
The project focuses on the role of Kidney Injury Molecule-1 (KIM-1) in kidney epithelial repair and its potential as a drug target for chronic kidney disease. The project involves extensive research on KIM-1, including its binding to fatty acid-bound albumin, intracellular consequences, and role in inflammation. The project is part of a renewal application building upon prior findings.