Award
NIH Reporter #11382256
Curing chronic Toxoplasma infection with novel and potent protease inhibitors
Recipient
University of Michigan at Ann Arbor
Award Amount
$616,867.00
Ceiling
$616,867.00
Awarded
July 23, 2026
Identifier
11382256
NIH/NIAID awarded approximately $616,867 for a project to develop novel protease inhibitors to cure chronic Toxoplasma infection, including drug development and infection eradication in a mouse model.
Description
The project aims to develop new drugs to cure chronic ocular Toxoplasma gondii infection. The project involves developing a structure-to-function model of TgCPL, optimizing lead inhibitors, and eradicating infection in a mouse model. Funded by NIH/NIAID.