Award
National Institute of Biomedical Imaging and Bioengineering 1R21EB037939-01
Engineering BV to efficiently deliver large genetic payloads
Recipient
Rice University
Award Amount
$413,182.00
Ceiling
$413,182.00
Awarded
August 11, 2025
Identifier
1R21EB037939-01
Award to Rice University by the National Institute of Biomedical Imaging and Bioengineering to engineer baculoviral vectors for delivering large genetic payloads, funded at $413,182 from 2025 to 2027.
Description
This project aims to engineer and optimize baculoviral (BV) vectors for efficient in vivo delivery of large DNA payloads, addressing challenges such as complement system inactivation and weak interactions with mammalian cell surface proteins. The project is funded by NIH grant PA-20-195, with a total award amount of $413,182, spanning from September 1, 2025, to August 31, 2027. The principal investigators are Caleb Bashor and Gang Bao from Rice University.