Award
National Institute of Biomedical Imaging and Bioengineering 5R21EB035312-04
Development of a contact-free assay to evaluate stored blood quality using ultrasound viscoelasticity techniques
Recipient
Johns Hopkins University
Award Amount
$172,175.00
Ceiling
$172,175.00
Awarded
February 20, 2026
Identifier
5R21EB035312-04
NIH-funded research project to develop and validate a contact-free ultrasound assay for assessing stored blood quality to improve transfusion safety and efficacy.
Description
This project aims to develop a point-of-care, contact-free assay using ultrasound viscoelasticity techniques to evaluate stored blood quality prior to transfusion, potentially transforming clinical practice by enabling a precision medicine approach to transfusion efficacy. The project involves optimizing ARFI ultrasound beam sequences, validating clinical relevance, and comparing ARFI metrics versus storage age as predictors of transfusion outcomes.