Award
National Institute on Aging 5R21AG086992-02
Genome-Wide CRISPR Activation: A Novel Strategy for Identifying Anti-Aging Targets
Recipient
Northeastern University
Award Amount
$196,400.00
Ceiling
$196,400.00
Awarded
March 24, 2025
Identifier
5R21AG086992-02
Development of a CRISPRa gene-activation toolkit for C. elegans to identify genes affecting aging and longevity, supporting anti-aging therapy research.
Description
This project aims to characterize and optimize a novel, time- and cost-efficient toolkit for gene activation in C. elegans using CRISPRa technology to identify genes that influence lifespan and health, facilitating the development of anti-aging therapies.