Award
National Institute of General Medical Sciences 5R35GM142774-05
Regulation of mitochondrial dynamics pathways in mammalian cells
Recipient
University of Colorado Denver, Aurora, CO
Award Amount
$383,699.00
Ceiling
$383,699.00
Awarded
March 25, 2025
Identifier
5R35GM142774-05
Research project funded by NIGMS to study mitochondrial dynamics in mammalian cells, aiming to elucidate mechanisms that impact cellular fitness and have implications for diseases and aging.
Description
This project aims to understand the mechanisms governing mitochondrial dynamics and the interplay between mitochondrial transport and other aspects of mitochondrial and cellular biology. It focuses on characterizing the function and regulation of trafficking protein isoforms in non-neuronal cells, exploring their multifunctionality including roles in mitochondrial metabolism and signaling, with implications for neurological and metabolic diseases, cancer, and aging.