Award
National Institute of Diabetes and Digestive and Kidney Diseases PA-23-271
Network Modeling of Dietary Effect on Host and Microbial Metabolism
Recipient
UNIVERSITY OF COLORADO DENVER
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
May 21, 2026
Identifier
PA-23-271
Award for developing a computational framework to analyze diet-microbe-host interactions using diverse biological and dietary data to understand disease mechanisms and aid therapeutic development.
Description
This project aims to develop a computational framework to analyze diet-microbe-host interactions at the compound-enzyme level, leveraging databases such as KEGG and FooDB. The work involves integrating genomic, microbiome, metabolomic, and dietary data from diverse datasets, including cohorts of people living with HIV in Zimbabwe and inflammatory bowel disease datasets. The goal is to facilitate the detection of diet-microbe-host interactions and contribute to understanding disease mechanisms and therapeutic development.