Award
National Eye Institute 5R01EY033731-03
IMPDH1 in photoreceptor function and disease
Recipient
University of Washington
Award Amount
$410,551.00
Ceiling
$410,551.00
Awarded
April 02, 2026
Identifier
5R01EY033731-03
Research project funded to study the role of IMPDH1 enzyme in photoreceptor health and disease, aiming to understand its function and impact of mutations causing retinal degeneration.
Description
This project focuses on understanding how mutations in the metabolic enzyme IMPDH1 cause dominant inherited photoreceptor degeneration. The research aims to determine the normal physiological role of IMPDH1 in photoreceptors and how this is affected in patients with degenerative retinal diseases due to IMPDH1 mutations.