Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5R21AR082620-02
A pilot trial of skin barrier restoration to reduce systemic inflammation
Recipient
University of California, San Francisco
Award Amount
$255,816.00
Ceiling
$255,816.00
Awarded
April 01, 2025
Identifier
5R21AR082620-02
A pilot clinical trial funded by NIAMS to assess whether restoring skin barrier function with moisturizers can reduce systemic inflammation in adults aged 70 and above, involving measures of inflammatory markers, skin barrier function, and microbiome diversity.
Description
This pilot study investigates the impact of moisturizers on age-associated skin barrier decline and inflammation. The study aims to determine measures of skin barrier function, systemic inflammation, microbiome role, and feasibility of moisturizer use in older adults.