Award
National Institute of General Medical Sciences 5R35GM153293-03
Mechanisms of gene regulation by long noncoding RNAs
Recipient
University of North Carolina Chapel Hill
Award Amount
$624,197.00
Ceiling
$624,197.00
Awarded
April 02, 2026
Identifier
5R35GM153293-03
Research project funded to study the mechanisms of gene regulation by long noncoding RNAs, focusing on their interaction with proteins and prediction of regulatory functions, with implications for disease and therapy.
Description
This research aims to determine how long noncoding RNAs (lncRNAs) and proteins interact to achieve specific gene regulatory outcomes and to develop new ways to predict the presence of regulatory functions in lncRNAs. The work is expected to reveal new and conserved mechanisms of gene regulation, disease etiologies, and therapeutic opportunities.