Award
National Institute of Dental and Craniofacial Research 5R01DE033009-04
Identifying the core transcriptional regulatory network initiating a tooth program
Recipient
University of Iowa, Iowa City, IA, United States
Award Amount
$446,175.00
Ceiling
$446,175.00
Awarded
May 27, 2026
Identifier
5R01DE033009-04
This NIH-funded research project studies the transcriptional regulatory networks involved in tooth development to enable stem cell-based regenerative therapies for tooth repair.
Description
The project aims to dissect molecular and cellular mechanisms of tooth initiation, focusing on core transcriptional regulatory networks that specify dental lamina within maxillary and mandibular ectoderm. The long-term goal is to develop regenerative therapies for tooth repair.