# NIH Reporter #1R16NS150184-01

p(UG) RNA Quadruplexes as Nucleators of Stress Granules and Modulators of TDP-43 Pathology in ALS

**Recipient:** University of Puerto Rico Medical Sciences

**Award Amount:** $745,000.00
**Ceiling:** $745,000.00

**Awarded:** September 10, 2026

**Identifier:** 1R16NS150184-01

A multiyear research award of $745,000 to University of Puerto Rico Medical Sciences for studying RNA quadruplexes and their role in ALS pathology.

### Description

The project focuses on RNA structure and neurodegenerative disease research, specifically ALS. The project involves RNA quadruplexes, stress granules, and TDP-43 pathology. The award is multiyear, with a total budget of $745,000. The project is managed by the University of Puerto Rico Medical Sciences.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11423777)