Award
National Heart, Lung, and Blood Institute 5K08HL169725-03
Transfer RNAs as novel mediators in acute lung injury
Recipient
Ohio State University, Columbus, OH, United States
Award Amount
$163,620.00
Ceiling
$163,620.00
Awarded
April 27, 2026
Identifier
5K08HL169725-03
Research project funded by the National Heart Lung and Blood Institute to study the role of tRNAs and TRMT1 in acute lung injury, aiming to find new therapeutic targets for ARDS.
Description
This project investigates the role of transfer RNAs (tRNAs) and their fragments in acute lung injury (ARDS). It explores how the methyltransferase TRMT1 regulates tRNA fragmentation and host defense mechanisms, aiming to identify novel therapeutic targets for ARDS.