Award
University of Pittsburgh 1F30AI197375-01
Mechanisms by which extracellular vesicles released by allografts promote anti-donor immunity
Recipient
University of Pittsburgh at Pittsburgh, Department of Surgery, United States
Award Amount
$55,114.00
Ceiling
$55,114.00
Awarded
April 03, 2026
Identifier
1F30AI197375-01
Research project awarded to study how extracellular vesicles from allografts promote anti-donor immunity, involving advanced imaging and molecular analysis techniques.
Description
This project focuses on characterizing graft-derived extracellular vesicles and their role in transplant rejection. The project involves in vivo imaging, proteomics, and transcriptomics analysis to understand EV cellular sources, cargo, and effects on immune cells.