Award
NIH Reporter #11415664
Vasculopathy and Systemic Sclerosis-Associated Interstitial Lung Disease
Recipient
Columbia University Health Sciences
Award Amount
$626,903.00
Ceiling
$626,903.00
Awarded
August 20, 2026
Identifier
11415664
Award for a research project at Columbia University Health Sciences to study systemic sclerosis-associated interstitial lung disease, focusing on microvasculature and lung function to develop new treatments.
Description
This project aims to elucidate the relationships between microvasculature, endothelial function, lung function, and ILD in adults with systemic sclerosis through a prospective cohort study. The study involves structural, functional, and molecular approaches, including single-cell RNA sequencing of circulating endothelial cells. The goal is to identify novel outcome measures and develop new treatments for SSc-ILD, with potential applicability to other fibrotic lung diseases.