Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5R21HD116113-02
Neural Mechanism of Impaired Satiation After Magel2 Mutation
Recipient
University of Arizona
Award Amount
$184,527.00
Ceiling
$184,527.00
Awarded
July 24, 2025
Identifier
5R21HD116113-02
This NIH-funded project investigates how Magel2 gene mutation affects neural mechanisms of satiation, aiming to understand and potentially control insatiable appetite in genetic disorders.
Description
Research to determine the neural mechanisms underlying impaired satiation focusing on CeA PKC-δ neurons and the Magel2 gene mutation, using in vivo calcium imaging and electrophysiology to assess effects and appetite suppression potential.