Award
National Institute of Neurological Disorders and Stroke 5R01NS139872-02
Development of photocaged DREADD agonists for high-efficiency, target-specific optical silencing of synaptic transmission
Recipient
University of California, San Diego, La Jolla, CA
Award Amount
$967,201.00
Ceiling
$967,201.00
Awarded
January 23, 2026
Identifier
5R01NS139872-02
The award funds the development of light-activated designer drugs to achieve precise, target-specific optical silencing of synaptic transmission in the brain, enhancing neuroscience research capabilities.
Description
This grant supports research on developing optochemogenetic tools for neural silencing using light-activated DREADD agonists, with potential applications in neuroscience research involving behavioral and neural activity analysis.