Award

NIH Reporter #5R01AI173138-04

Clinical Impact of the Cefazolin Inoculum Effect

Recipient

Methodist Hospital Research Institute, Houston, TX, United States

Award Amount

$425,805.00

Ceiling

$425,805.00

Awarded

August 14, 2026

Identifier

5R01AI173138-04

A research grant awarded to study the clinical impact of the cefazolin inoculum effect on MSSA bacteremia and to validate a rapid diagnostic tool internationally to improve treatment outcomes.

Description

This NIH grant project focuses on assessing the clinical impact of the cefazolin inoculum effect (CzIE) on methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia outcomes and validating a rapid diagnostic assay across international sites to optimize antibiotic use and improve patient outcomes.

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