Award
National Cancer Institute 11181592
Deciphering the Dynamic Evolution of the Tumor-Neural Interface
Recipient
Massachusetts Institute of Technology
Award Amount
$428,797.00
Ceiling
$428,797.00
Awarded
September 22, 2025
Identifier
11181592
This award funds a project at MIT to develop computational models of glioblastoma tumor dynamics, focusing on tumor-neuronal interactions and mechanisms of tumor invasion and progression.
Description
The project aims to develop computational models to map and predict tumor dynamics in glioblastoma by leveraging high-content systems-level measurements at molecular, microscopic, and macroscopic scales with spatial resolution. The focus is on elucidating networks that coordinate the tumor-neuronal interface, particularly how glioblastoma cells form synaptic connections with neural cells, promoting tumor invasion and progression.