Award
National Institutes of Health 11249675
Polycystin-1 C terminal tail cleavage: Mechanisms and meaning
Recipient
Yale University
Award Amount
$640,797.00
Ceiling
$640,797.00
Awarded
December 12, 2025
Identifier
11249675
This award funds research on the cleavage of the PC1 protein and its impact on cystic kidney disease, with goals to understand disease mechanisms and develop potential treatments for ADPKD.
Description
Research project investigating the mechanisms of PC1 cleavage and its role in autosomal dominant polycystic kidney disease (ADPKD), aiming to identify new therapeutic targets.