Award
National Institute of Allergy and Infectious Diseases 1R21AI194047-01
Autoimmunity, calorie restriction, and core body temperature
Recipient
SAN DIEGO BIOMEDICAL RESEARCH INSTITUTE, SAN DIEGO, CA, UNITED STATES
Award Amount
$541,500.00
Ceiling
$541,500.00
Awarded
June 17, 2025
Identifier
1R21AI194047-01
The project investigates how calorie restriction and body temperature reduction affect lupus autoimmunity in mouse models, aiming to understand the mechanisms behind CR-mediated inhibition of lupus pathogenesis.
Description
This project explores the effects of caloric restriction and thermoneutral housing on lupus autoimmunity and aging in mouse models, with potential translational implications for human health.