Award
National Cancer Institute 5F30CA298567-02
Molecular and Spatial Factors Defining Tumor-specific CD8 T Cell States in Cold Tumors
Recipient
WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY, UNITED STATES
Award Amount
$54,969.00
Ceiling
$54,969.00
Awarded
July 14, 2026
Identifier
5F30CA298567-02
Research project focused on understanding the molecular and spatial factors influencing tumor-specific CD8 T cell states in cold tumors to improve immunotherapy responses.
Description
This project utilizes clinically relevant mouse models and patient samples to elucidate the molecular and spatial factors that determine tumor-specific CD8 T cell states associated with cold immune dessert tumor phenotypes. The research aims to provide insights into mechanisms impairing CD8 T cell infiltration into cold tumors and factors related to responsiveness to immunotherapies.