Award
NIH Reporter #5F31CA294869-02
Investigating the role of tumor-intrinsic BCAT1 in HCC growth and anti-tumor immunity
Recipient
University of Pennsylvania
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
July 06, 2026
Identifier
5F31CA294869-02
The National Cancer Institute awarded the University of Pennsylvania funding for research on the role of BCAT1 in hepatocellular carcinoma growth and tumor immunity.
Description
Project investigating whether BCAT1 promotes hepatocellular carcinoma growth and suppresses anti-tumor immunity by reducing branched-chain amino acid availability to immune cells. The work includes in vitro and in vivo studies of BCAT1 knockdown, tumor growth, and immune cell populations.