Award
National Heart, Lung, and Blood Institute 5R01HL153974-05
Altered inflammatory response associated with acquired DNMT3A mutations
Recipient
Not specified
Award Amount
$577,352.00
Ceiling
$577,352.00
Awarded
April 14, 2025
Identifier
5R01HL153974-05
NIH awarded $577,352 to study how DNMT3A mutations affect inflammation and to develop treatments for related diseases using stem cell-derived myeloid cells.
Description
The project focuses on studying the impact of DNMT3A mutations on inflammation using human pluripotent stem cell-derived myeloid cells. The research aims to identify epigenetic mechanisms and develop strategies to prevent and treat related diseases.