Award
National Cancer Institute 11047109
Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers
Recipient
UNIV OF NORTH CAROLINA CHAPEL HILL
Award Amount
$717,245.00
Ceiling
$717,245.00
Awarded
July 14, 2025
Identifier
11047109
Award for research on autophagy in RAS-driven cancers, aiming to understand pathways and resistance mechanisms, funded by the National Cancer Institute.
Description
The project focuses on autophagy in RAS-driven cancers, with specific aims to dissect autophagy pathways and evaluate resistance mechanisms in pancreatic ductal adenocarcinoma. The project involves clinical evaluation of autophagy inhibitors such as hydroxychloroquine in combination with other pathway inhibitors.