Award

National Institute of Allergy and Infectious Diseases 5U01AI172853-04

Development of a Novel Therapeutic for Mitigating Radiation-Induced Microbiome Dysbiosis and Acute Gastrointestinal Syndrome

Recipient

Columbia University Health Sciences

Award Amount

$495,545.00

Ceiling

$495,545.00

Awarded

January 09, 2026

Identifier

5U01AI172853-04

NIH awarded Columbia University $495,545 to develop MIIST305, a novel therapeutic to counteract radiation-induced gastrointestinal syndrome by preserving gut microbiota and reducing inflammation, addressing a critical need for FDA-approved radiation GI injury treatments.

Description

Development of a novel GI-targeted therapeutic drug (MIIST305) to mitigate radiation-induced gastrointestinal injury by maintaining gut microbiota balance and reducing inflammation, aiming to develop an FDA-approved medical countermeasure for radiation public health emergencies.

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