Award

NIH Reporter #3U01AI158460-05S1

Mechanistic clinical trial of blocking the IL-4/13 axis in asthmatics precision phenotyped in an aeroallergen challenge chamber before, during and after receipt of dupilumab

Recipient

UNIVERSITY OF TEXAS HLTH SCIENCE CENTER

Award Amount

$490,019.00

Ceiling

$490,019.00

Awarded

August 19, 2026

Identifier

3U01AI158460-05S1

A clinical trial funded by NIAID to investigate the effects of dupilumab on allergic asthma and rhinitis through detailed mechanistic studies.

Description

This project involves a mechanistic clinical trial to study the effects of dupilumab on allergic asthma and rhinitis, with detailed assessments pre-, during, and post-treatment, including mechanistic studies of airway and systemic compartments.

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