# NIH Reporter #1UG3NS149390-01

Advancing HD Therapeutics

**Recipient:** University of Massachusetts Medical School Worcester

**Award Amount:** $1,038,135.00
**Ceiling:** $1,038,135.00

**Awarded:** September 02, 2026

**Identifier:** 1UG3NS149390-01

The award funds research into a trivalent RNA interference therapy designed to silence three Huntington’s disease targets. The project will optimize the system and test its safety and effectiveness in animal models.

### Description

Blueprint Neurotherapeutics grant to develop and evaluate a trivalent siRNA system that simultaneously targets three disease-related RNAs in Huntington’s disease.

[View original record](https://reporter.nih.gov/search/47CiHD0bJ0u2LtDABS0zbg/project-details/11372655)