Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK078184-17
Factors Controlling Metabolic Flux in the Liver
Recipient
UT SOUTHWESTERN MEDICAL CENTER
Award Amount
$508,728.00
Ceiling
$508,728.00
Awarded
February 24, 2026
Identifier
5R01DK078184-17
NIH funded research project led by UT Southwestern Medical Center to study metabolic flux in the liver related to obesity and liver disease.
Description
The project investigates mitochondrial metabolism's role in obesity-related liver disease using stable isotope tracer methods, NMR, MS, and knockout mice, focusing on redox state, antioxidant capacity, and metabolic compartmentation.