Award
National Institute of Allergy and Infectious Diseases 5R01AI152766-05
Glycopeptide-specific helper T cells eliciting protective humoral immunity against HIV - Resubmission
Recipient
Emory University
Award Amount
$494,100.00
Ceiling
$494,100.00
Awarded
February 13, 2026
Identifier
5R01AI152766-05
The award supports research at Emory University to develop a protective HIV vaccine by studying helper T cell responses to glycan epitopes on the HIV gp120 protein, aiming to enhance immune response and vaccine design.
Description
This project proposes an innovative approach to HIV vaccine research, focusing on the human CD4+ T cell repertoire and glycan epitopes on gp120, aiming to develop a new generation of protective HIV vaccines. It investigates adaptive immune mechanisms induced by the HIV-1 surface glycoprotein to create a platform for highly immunogenic and protective vaccines.