Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK133440-03
Mechanisms and Selective Modulation of PPARγ for the Treatment of Podocytopathies
Recipient
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Award Amount
$249,639.00
Ceiling
$249,639.00
Awarded
April 23, 2025
Identifier
5R01DK133440-03
NIH awarded a grant to study selective modulation of PPARγ as a targeted therapy for nephrotic syndrome, aiming to improve treatment outcomes and reduce side effects in kidney disease patients.
Description
This NIH grant project aims to identify podocyte-specific transcriptional targets of PPARγ and evaluate the therapeutic benefits of selective modulation for nephrotic syndrome treatment, focusing on reducing proteinuria and podocyte injury with fewer side effects.