Award
NIH Reporter #5R01AI192971-02
Mechanistic and Structural Insights into Intraflagellar Transport in Leishmania
Recipient
Harvard Medical School
Award Amount
$575,932.00
Ceiling
$575,932.00
Awarded
August 21, 2026
Identifier
5R01AI192971-02
NIH grant awarded to Harvard Medical School to study intraflagellar transport mechanisms in Leishmania, aiming to understand flagella biology and identify therapeutic targets for leishmaniasis.
Description
This project aims to elucidate mechanisms of intraflagellar transport (IFT) in Leishmania, providing insights into flagella biology and identifying potential therapeutic targets for leishmaniasis. The research will utilize structural biology, live-cell imaging, proteomics, and bioinformatics to study IFT trains along microtubules in Leishmania tarentolae.