Award
NIH Reporter #3R01DK131497-05S1
Mechanisms of HIV persistence in the kidney
Recipient
Duke University
Award Amount
$817,376.00
Ceiling
$817,376.00
Awarded
August 05, 2026
Identifier
3R01DK131497-05S1
NIH grant awarded to Duke University to study HIV persistence in the kidney, focusing on viral reservoirs, reactivation potential, and implications for HIV cure strategies.
Description
This NIH grant project aims to understand the mechanisms and implications of HIV infection and persistence in the kidney, including the potential for viral reactivation and clonal expansion of infected renal epithelial cells. The study will analyze samples from people with HIV undergoing kidney transplantation and ART interruption to inform cure strategies and renal pathogenesis.