Award
NIH Office of the Director 5K01OD034070-03
Spatialomics and quantitative MRI of ischemic injury in a piglet model of Legg-Calve-Perthes disease
Recipient
University of Minnesota
Award Amount
$132,408.00
Ceiling
$132,408.00
Awarded
August 21, 2025
Identifier
5K01OD034070-03
Research project funded by NIH to study cell signaling changes in Legg-Calve-Perthes disease using spatialomics and MRI in a piglet model, aiming to understand disease biology and evaluate treatments.
Description
This project uses a piglet model of Legg-Calvé-Perthes disease (LCPD), a pediatric disease affecting the hip, to determine the cell signaling changes that underlie tissue damage observed on the microscopic level and with MRI. The goal is to better understand the biology of the disease and evaluate potential treatments suitable for children.