Award
National Institute on Aging 5R01AG078734-05
Deciphering tau phosphorylation and Abeta/tau strain interactions in Alzheimer’s pathogenesis
Recipient
University of Florida
Award Amount
$448,122.00
Ceiling
$448,122.00
Awarded
June 01, 2026
Identifier
5R01AG078734-05
Research project funded by the National Institute on Aging to study tau phosphorylation and amyloid beta interactions in Alzheimer's disease using mouse models, aiming to understand disease mechanisms and progression.
Description
This project investigates the mechanisms of Aβ deposition and tau misfolding in Alzheimer’s disease, focusing on tau phosphorylation sites and amyloid deposit types. It aims to elucidate how these factors contribute to tau pathology and neurofibrillary tangles, using mouse models and AAV technology.