# NIH Reporter #3P01AI186817-02S1

Mitigator Efficacies after Realistic Improvised Nuclear Device (IND) Exposure: MERIE

**Recipient:** Columbia University Health Sciences

**Award Amount:** $196,911.00
**Ceiling:** $196,911.00

**Awarded:** September 10, 2026

**Identifier:** 3P01AI186817-02S1

The project addresses the critical need for effective radiation countermeasures against IND scenarios, focusing on the unique and more realistic exposure conditions involving high dose rates and neutrons, and aims to determine the efficacy of existing mitigators and explore combination strategies.

### Description

This project aims to evaluate the effectiveness of radiation mitigators developed for conventional x-ray exposures against IND-specific radiations, including very high dose rate exposures and neutrons, using Columbia University's unique radiation sources. The research will also explore the potential for combining multiple mitigators (polypharmacy) to enhance protective effects.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11554183)