Award
National Institute of Allergy and Infectious Diseases (NIAID) 5R37AI053531-23
Picornavirus Genome Replication
Recipient
University of North Carolina at Chapel Hill
Award Amount
$534,015.00
Ceiling
$534,015.00
Awarded
January 16, 2026
Identifier
5R37AI053531-23
Research project funded by NIAID to study how poliovirus manipulates host cell membranes for viral replication, aiming to uncover mechanisms of membrane biogenesis and lipid remodeling during infection.
Description
This project focuses on understanding the mechanisms of membrane biogenesis, function, and trafficking during picornavirus infection, specifically poliovirus (PV). The research aims to elucidate how PV hijacks host cell mechanisms to remodel lipid membranes, which is critical for viral replication and assembly.