Award
National Institute of Environmental Health Sciences 4R44ES036902-02
Development of a Comprehensive Hen's Egg Model for Genotoxicity Testing
Recipient
LITRON LABORATORIES, LTD.
Award Amount
$1,199,633.00
Ceiling
$1,199,633.00
Awarded
July 23, 2025
Identifier
4R44ES036902-02
NIH awarded approximately $1.2 million to develop a hen's egg model for genotoxicity testing, focusing on non-animal methods and advanced imaging techniques.
Description
The project aims to develop, optimize, and validate a hen’s egg model for assessing chemicals for DNA damage potential. It involves advanced techniques such as flow cytometry and high content imaging and addresses regulatory needs for an accurate, metabolically-active in vitro genotoxicity assay. The project is funded by NIH as part of a shift towards non-animal testing methods in toxicology, with a duration from August 10, 2024, to July 31, 2027.