Award
NIH Reporter #5R00AG075238-05
Elucidating sex-specific risk for Alzheimer's disease through state-of-the-art genetics and multi-omics
Recipient
Washington University
Award Amount
$236,497.00
Ceiling
$236,497.00
Awarded
August 06, 2025
Identifier
5R00AG075238-05
Research project funded by the National Institute on Aging to investigate sex-specific genetic factors in Alzheimer's disease through advanced genetics and multi-omics techniques.
Description
This project aims to discover sex-specific genetic risk variants and protein changes associated with Alzheimer's disease using innovative approaches including large sex-stratified GWAS, exploration of the X chromosome, and multi-omics data integration. The findings will provide insights into disease pathophysiology, identify novel risk factors, and uncover potential drug targets.