Award
NIH Reporter #5F30DK142445-02
Uncovering the mechanistic drivers of hepatic dysfunction in LIPT1 deficiency
Recipient
UT SOUTHWESTERN MEDICAL CENTER
Award Amount
$44,267.00
Ceiling
$44,267.00
Awarded
April 24, 2026
Identifier
5F30DK142445-02
Research project to understand hepatic dysfunction mechanisms in LIPT1 deficiency and test dietary interventions.
Description
This project aims to define the role of lipoylation in liver metabolism, investigate drivers of hepatic disease in lipoylation deficiency, and trial targeted dietary supplementation to attenuate metabolic dysfunction.