Award
National Institute of Diabetes and Digestive and Kidney Diseases 5U54DK137329-04
Physiology Core
Recipient
University of Pittsburgh at Pittsburgh, PA, United States
Award Amount
$238,773.00
Ceiling
$238,773.00
Awarded
July 07, 2026
Identifier
5U54DK137329-04
The Physiology Core NIH grant supports advanced research technologies and expertise to study kidney function at molecular and cellular levels, facilitating kidney research through specialized subcores and collaboration.
Description
The Physiology Core provides a series of graded technologies and expertise to investigators who wish to address fundamental questions about transport processes that occur in the tubular structures of the nephron and other relevant systems. The Core offers expertise and state-of-the-art technologies for studying the function and regulation of transport and other membrane resident proteins with progressive degrees of complexity from single molecules to model systems to native epithelia. It includes three Subcores: Single Tubule and Microperfusion, Electrophysiology, and Live-Cell Imaging, providing tools and technologies to study transport proteins and associated regulatory pathways in nephron segments, model systems, and native epithelia. The Core collaborates with the O’Brien Consortium to share specialized resources and technologies throughout the kidney research community, aiming to lower barriers for early-stage investigators and advance kidney research nationwide.