Award
National Institute of Allergy and Infectious Diseases 5R01AI179188-04
Multiscale Computational Microscopy of HIV-1
Recipient
University of California, San Diego
Award Amount
$654,097.00
Ceiling
$654,097.00
Awarded
July 03, 2026
Identifier
5R01AI179188-04
NIH awarded a research grant to University of California, San Diego for advanced molecular dynamics simulations studying HIV-1 envelope protein dynamics to aid vaccine and drug design.
Description
This is a multi-year NIH research project focused on HIV-1 Env protein dynamics using multiscale all-atom molecular dynamics simulations as a computational microscope to explore the dynamics and interactions of the HIV-1 envelope protein (Env). The project aims to provide insights unattainable with current experimental techniques, optimize immunogen design, and identify druggable sites in Env.