Award
National Institute of Neurological Disorders and Stroke 5R01NS122119-05
Development of quantitative optical tools to continuously monitor cerebral autoregulation, blood flow, oxygenation and inflammation during pediatric extracorporeal life support
Recipient
UT Southwestern Medical Center
Award Amount
$616,590.00
Ceiling
$616,590.00
Awarded
March 23, 2026
Identifier
5R01NS122119-05
The award funds research to develop and test continuous optical monitoring tools to assess cerebral autoregulation and inflammation in pediatric ECMO patients, aiming to predict neurological injury and improve patient outcomes.
Description
This project aims to develop continuous non-invasive bedside monitors for critically ill patients, specifically to test if optical monitoring can predict neurological injury during ECMO and to correlate optical metrics with neuroinflammatory biomarkers. The goal is to improve neuroprotection in ECMO patients through innovative optical monitoring techniques, potentially reducing morbidity and mortality.