Award
National Institute of Allergy and Infectious Diseases 5U19AI181977-03
Research Project 2: Antigen design and immunological evaluation
Recipient
Albert Einstein College of Medicine, Bronx, NY, United States
Award Amount
$1,836,948.00
Ceiling
$1,836,948.00
Awarded
July 20, 2026
Identifier
5U19AI181977-03
The award funds a research project focused on designing and evaluating vaccine antigens against nairo-, hanta-, and paramyxoviruses using advanced antigen engineering techniques to develop optimized vaccine immunogens with pandemic potential.
Description
This project aims to optimize vaccine immunogens for nairo-, hanta-, and paramyxoviruses, providing a roadmap for vaccine development against these viruses with pandemic potential. The project involves structure-based antigen design, evaluation of antigenicity and protective efficacy, characterization of humoral immune responses, and evaluation of T cell responses to engineered antigens.