Award
National Cancer Institute RFA-CA-23-028
Developing ribosome biogenesis inhibitors for the prevention of cancer
Recipient
UT SOUTHWESTERN MEDICAL CENTER
Award Amount
$292,886.00
Ceiling
$292,886.00
Awarded
May 14, 2026
Identifier
RFA-CA-23-028
This award funds a project to develop inhibitors targeting ribosome biogenesis to prevent cancer, using novel assay platforms and testing in mouse models, supported by the National Cancer Institute.
Description
The project aims to develop inhibitors of ribosome biogenesis to prevent cancer. It involves innovative platforms called ribo-SNAP and SidBait to identify and develop ribosome biogenesis inhibitors as effective anti-cancer agents. The project includes screening natural product libraries, identifying compound targets, and testing in mouse models to prevent liver tumor formation. The project duration is from May 21, 2024, to April 30, 2027.