Award
NIH Reporter #1F32AA032721-01A1
Examining somatostatin receptor pathways following binge drinking: a focus on PFC-->PAG projections
Recipient
Pennsylvania State University, The, University Park, PA
Award Amount
$76,780.00
Ceiling
$76,780.00
Awarded
June 16, 2026
Identifier
1F32AA032721-01A1
A fellowship project studying how binge drinking affects somatostatin receptor pathways in brain projections from the prefrontal cortex to the periaqueductal gray, using electrophysiology and neuroimaging in mice.
Description
This fellowship aims to investigate the role of somatostatin (SST) signaling onto prefrontal cortex (PFC) outputs to the periaqueductal gray (PAG), a pathway involved in pain and behavior modulation, altered in Alcohol Use Disorder (AUD). Using a mouse model of voluntary binge-like alcohol consumption, the study examines alcohol-induced changes in SST function and neuronal signaling.