Award
NIH Reporter #5R61CA278402-03
Intersectional genetics-based biosensors for dormant cancer cells
Recipient
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NEW YORK, NY
Award Amount
$213,638.00
Ceiling
$213,638.00
Awarded
September 05, 2025
Identifier
5R61CA278402-03
The award funds the development of a biosensor for dormant cancer cells using intersectional genetics and synthetic biology to enable identification and manipulation of these cells in vivo, aiming to improve understanding and treatment of cancer metastasis.
Description
This project proposes to devise a dormant cancer cell biosensor by using intersectional genetics and synthetic biology technologies that will allow the identification, molecular profiling, and genetic manipulation of dormant cancer cells in vivo.