Award
National Institute on Minority Health and Health Disparities 5R01MD014618-06
The impact of enculturation on the epigenetic relationship between chronic stress and hypertension in Yup'ik Alaska Native people
Recipient
Oregon Health & Science University, Portland, OR
Award Amount
$525,769.00
Ceiling
$525,769.00
Awarded
January 15, 2026
Identifier
5R01MD014618-06
Research project studying how cultural factors affect blood pressure regulation and related biological pathways in Yup'ik Alaska Native people to inform health interventions.
Description
The proposed research aims to identify molecular mechanisms linking the protective role of culture to blood pressure regulation, a major risk factor for stroke among Yup'ik Alaska Native people. The study will examine how enculturation and biculturalism influence blood pressure and related biological pathways, including inflammation, epigenetic regulation, and telomere length, to develop culturally effective interventions.